No.
The x and y values say where to place objects. This is like graph paper. The (0,0) location is the upper left corner of the drawing area. Y values increase going down.
Distance is measured in pixels. A pixel is one of the graph paper squares that the video screen has been (conceptually) divided into. If your monitor is set to a resolution of 1920 by 1080, then the whole screen is divided into 1920 horizontal squares and 1080 vertical squares. A window will usually cover only part of that area, perhaps an area 400 pixels horizontal by 300 vertical. It is the responsibility of the graphics card and its driver to implement this idea of graph paper on the actual electronics of your computer system.
A pixel is not one of the little, glowing dots of phosphor on the monitor screen. A pixel is a conceptual measurement. Depending on the resolution you are using, an image pixel may correspond to several of these dots or a fraction of one dot.
The resolution of a monitor is the number of pixels it displays horizontally and vertically.
Say that a window is displayed in a rectangle of 300 by 300 pixels. Does the actual size (as measured in inches) of the rectangle depend on the resolution of the monitor?